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Thermo Fisher

CellInsight CX5 High Content Screening (HCS) Platform

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The Thermo Scientific™ CellInsight™ CX5 High Content Screening (HCS) Platform is a fast, simple-to operate, automated cellular imaging and analysis benchtop platform designed for quantitative microscopy. The CellInsight CX5 HCS Platform offers a cost effective, but powerful way to quickly automate quantitative cellular and subcellular imaging.

Features of the CellInsight CX5 HCS Platform
• Easy to Use—quickly build and optimize image-based assays with included Thermo Scientific™ HCS Studio™ Cell Analysis Software
• Flexible—designed to work with or without fluorescent labeling: The CellInsight CX5 HCS Platform can use transmitted light, as well as fluorescence, to allow users to focus on visible and/or fluorescent targets
• Affordable—automated high content imaging for all budgets
• High quality optics—Light sources, lenses, filters, and CCD detector from the top names in imaging. The five color light engine insures accuracy and stability of source lighting.
• Virtually maintenance–free operation due to state-of-the-art design and construction.
• Performance—scan and analyze a 96-well plate in under four minutes
• Compact—fits on a bench and is less than 2 ft. on all sides

Capabilities:
• Make intracellular to multicellular morphology measurements while measuring intensity of specific reporter molecules.
• Collect only the images and data you select and make multiple measurements per object, over time, if desired
• Measure subpopulations and reject undesired objects automatically
• Comprehensive pre-validated and user configurable image analysis without user scripting or programming
• Exploratory assay development tools and specific biology optimized tools built into the HCS Studio™ Cell Analysis Software
• Define biological thresholds for outputs based on control populations
• Ability to create multi-parameter gates from individual output measurements

Hardware and Software:
• Stable, reliable light source reduces variability, increases data quality, and decreases operating costs
• Fluorescence options which include near-IR wavelength and compatibility with many common fluorochromes and fluorescent proteins
• • Proprietary Thermo Scientific™ AccuFocus™ System is fast, yet flexible, for imaging cells, organelles, and low contrast targets
• Unique intelligent acQuisition (iQ) real time analysis feedback to optimize image collection and data quality
• HCS Studio Cell Analysis Software is an integrated instrument control, visualization and analysis software package for novice to advanced users
• Features Thermo Scientific™ Store Express Image and Database Software using a 10GB SQL™ database
• Software output features image/data portability so results can be imported into third-party software for documentation
• Compatible with SBS standard microplates (6-1536 well) and slides

Compatible with Thermo Scientific™ Orbitor RS Plate Mover and other Thermo Scientific™ Laboratory Automation Solutions

Specification

Color:

Blue, Far-Red, Green, Near-Infrared, Red

Compatible Products:

Thermo Scientific™ HCS Studio Cell Analysis Software, Thermo Scientific™ Orbitor™ RS Plate Mover

Data Output:

BIN, BMP, C01, CSV, DIB, FCS 3.1, GIF Files, ICE, JPG Files, PNG Files, PZFX, TIFF Files, XLSX

Detection Method:

Brightfield, Fluorescent

Dimensions:

41.4 cm (16.3 in) (W) x 37.2 cm (14.6 in) (H) x 59.4 cm (23.4 in) (D)

Display Interface:

24" High-resolution widescreen monitor

Excitation (nm):

386, 485, 560, 650, 740

Excitation⁄Emission (nm):

386⁄440, 485⁄521, 560⁄607, 650⁄694, 740⁄809

External Computer:

Windows 7™ 64-bit PC with quad core 3.7GHz processor, 8GB RAM, and 500GB Hard Drive

For Use With (Equipment):

Thermo Scientific™ HCS Studio Cell Analysis Software, Thermo Scientific™ Orbitor™ RS Plate Mover

Format:

1536-well plate, 24-well plate, 384-well plate, 6-well plate, 8 wells, 96-well plate, Slide(s)

High Throughput Compatibility:

Automated Protocols, High Throughput-Compatible, Multiplexing

Input Voltage:

120V

Instrument Memory:

8GB RAM

Objectives:

Additional Objectives Available, Low and High NA, Single Position 2x-20x

Operating Environment:

Permissible ambient temperature range during operation : + 18 deg C to + 25 deg C, Permissible relative humidity during operation (noncondensing): > 75% at 30 deg C

Operating System:

Windows 7

Optics:

CCD Camera, LED, solid-state 5-color light engine

Power Requirements:

300 W

Product Line:

CellInsight™

Product Size:

1 each

Software Compatibility:

Thermo Scientific™ HCS Studio™ Cell Analysis Software, Thermo Scientific™ Store™ Image and Database Management Software

Weight:

45 kg


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